The Stat4Onc Annual Symposium is a venue for interdisciplinary dialogue among clinical and quantitative scientists about cancer clinical trials. We seek participation by researchers from academia, industry, and regulatory agencies to share new research, discuss novel ideas, ask questions, and provide solutions for cancer clinical trials. Oncologists and statisticians can exchange views on trial design and conduct, drug development, and translation to patient care. Topics for this symposium include training for new generation of statisticians and clinicians, translational and precision oncology, master protocols, pediatric oncology research and drug development, populational cancer research, biomarkers and subgroups, real world data/evidence, and engagement of under-representative population in oncology research.